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SDS-PAGE

CD48 / SLAMF2 / BCM1 recombinant protein

Recombinant Rat CD48 / SLAMF2 / BCM1 Protein (His tag)

Gene Names
Cd48; SLAMF2
Purity
> 95 % as determined by SDS-PAGE
Synonyms
CD48 / SLAMF2 / BCM1; Recombinant Rat CD48 / SLAMF2 / BCM1 Protein (His tag); CD48; Bcm-1; CD48 / SLAMF2 / BCM1 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
240
Application Notes
The recombinant rat CD48 comprises 205 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of the recombinant protein is approximately 38-43 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Phe 23
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for CD48 / SLAMF2 / BCM1 recombinant protein
Background: Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

Description: A DNA sequence encoding the rat CD48 (P10252) (Met1-Arg216) was expressed, fused with a polyhistidine tag at the C-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,680 Da
NCBI Official Full Name
CD48 antigen
NCBI Official Synonym Full Names
Cd48 molecule
NCBI Official Symbol
Cd48
NCBI Official Synonym Symbols
SLAMF2
NCBI Protein Information
CD48 antigen
UniProt Protein Name
CD48 antigen
UniProt Gene Name
Cd48
UniProt Synonym Gene Names
Bcm-1; SLAMF2

NCBI Description

plays a role in mast cell activation and response to Mycobacterium tuberculosis [RGD, Feb 2006]

Uniprot Description

CD48: Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.

Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 13q24

Cellular Component: anchored to plasma membrane; external side of plasma membrane; lipid raft; membrane; plasma membrane; protein complex

Molecular Function: antigen binding

Biological Process: mast cell activation; signal transduction; T cell activation

Research Articles on CD48 / SLAMF2 / BCM1

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Product Notes

The CD48 / SLAMF2 / BCM1 cd48 (Catalog #AAA2547368) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant rat CD48 comprises 205 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of the recombinant protein is approximately 38-43 kDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the CD48 / SLAMF2 / BCM1 cd48 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD48 / SLAMF2 / BCM1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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