Flow Cytometry (FC/FACS)
(Flow cytometric analysis of CD48 expression on spleen lymphocytes. BALB/c splenocytes were treated with Mouse BD Fc Block' purified anti-CD16/CD32 mAb 2.4G2 and stained with FITC-conjugated anti-Mouse CD48 (50415-R341-C). The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.)
Rabbit anti-Mouse CD48 Monoclonal Antibody | anti-CD48 antibody
Recombinant Anti-CD48 Antibody (FITC), Rabbit Monoclonal
Gene Names
Cd48; BCM1; BLAST; Bcm-1; BLAST1; SLAMF2; Sgp-60; BLAST-1; MEM-102; AI449234; AW610730
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
CD48; Monoclonal Antibody; Recombinant Anti-CD48 Antibody (FITC); Rabbit Monoclonal; CD48/SLAMF2 Antibody (FITC); Rabbit MAb; CD48 molecule; Anti-AI449234 Antibody; Anti-AW610730 Antibody; Anti-Bcm-1 Antibody; Anti-BCM1 Antibody; Anti-BLAST Antibody; Anti-BLAST-1 Antibody; Anti-BLAST1 Antibody; Anti-MEM-102 Antibody; Anti-Sgp-60 Antibody; Anti-SLAMF2 Antibody; anti-CD48 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
341
Specificity
Mouse CD48/SLAMF2
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Concentration
10ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-CD48 antibody
Flow Cytometry (FC/FACS/FCM)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse CD48 protein
Conjugation
FITC
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD48/SLAMF2 (rM CD48/SLAMF2) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of CD48 expression on spleen lymphocytes. BALB/c splenocytes were treated with Mouse BD Fc Block' purified anti-CD16/CD32 mAb 2.4G2 and stained with FITC-conjugated anti-Mouse CD48 (50415-R341-C). The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of CD48 expression on spleen lymphocytes. BALB/c splenocytes were treated with Mouse BD Fc Block' purified anti-CD16/CD32 mAb 2.4G2 and stained with FITC-conjugated anti-Mouse CD48 (50415-R341-C). The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.)
Related Product Information for anti-CD48 antibody
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
Product Categories/Family for anti-CD48 antibody
References
Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,383 Da
NCBI Official Full Name
CD48 antigen
NCBI Official Synonym Full Names
CD48 antigen
NCBI Official Symbol
Cd48
NCBI Official Synonym Symbols
BCM1; BLAST; Bcm-1; BLAST1; SLAMF2; Sgp-60; BLAST-1; MEM-102; AI449234; AW610730
NCBI Protein Information
CD48 antigen; HM48-1; BCM1 surface antigen; MRC OX-45 surface antigen
UniProt Protein Name
CD48 antigen
Protein Family
UniProt Gene Name
Cd48
UniProt Synonym Gene Names
Bcm-1; SLAMF2
UniProt Entry Name
CD48_MOUSE
Uniprot Description
CD48: Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
Protein type: Membrane protein, GPI anchor
Cellular Component: protein complex; anchored to plasma membrane; membrane; plasma membrane; integral to membrane; lipid raft; external side of plasma membrane
Molecular Function: protein binding; receptor activity; antigen binding
Biological Process: T cell activation; signal transduction; mast cell activation
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Product Notes
The CD48 cd48 (Catalog #AAA8111539) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-CD48 Antibody (FITC), Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD48 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the CD48 cd48 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD48, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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