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Membrane cofactor protein (CD46) Recombinant Protein | CD46 recombinant protein

Recombinant Pig Membrane cofactor protein (CD46)

Gene Names
CD46; MCP
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Membrane cofactor protein (CD46); Recombinant Pig Membrane cofactor protein (CD46); Membrane cofactor protein; CD_antigen=; CD46; CD46 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
45-329
Sequence
CDEPPK FESMRPQFLN TTYRPGDRVE YECRPGFQPM VPALPTFSVC QDDNTWSPLQ EACRRKACSN LPDPLNGQVS YPNGDMLFGS KAQFTCNTGF YIIGAETVYC QVSGNVMAWS EPSPLCEKIL CKPPGEIPNG KYTNSHKDVF EYNEVVTYSC LSSTGPDEFS LVGESSLFCI GKDEWSSDPP ECKVVKCPYP VVPNGEIVSG FGSKFYYKAE VVFKCNAGFT LHGRDTIVCG ANSTWEPEMP QCIKDSKPTD PPATPGPSHP GPPSPSDASP PKDAESLDG
Sequence Length
285
Species
Sus scrofa (Pig)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,944 Da
NCBI Official Full Name
membrane cofactor protein
NCBI Official Symbol
CD46
NCBI Official Synonym Symbols
MCP
NCBI Protein Information
membrane cofactor protein; CD46 complement regulatory protein
UniProt Protein Name
Membrane cofactor protein
Protein Family
UniProt Gene Name
CD46
UniProt Synonym Gene Names
MCP
UniProt Entry Name
MCP_PIG

Uniprot Description

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. May act as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.

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Product Notes

The CD46 cd46 (Catalog #AAA1003252) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 45-329. The amino acid sequence is listed below: CDEPPK FESMRPQFLN TTYRPGDRVE YECRPGFQPM VPALPTFSVC QDDNTWSPLQ EACRRKACSN LPDPLNGQVS YPNGDMLFGS KAQFTCNTGF YIIGAETVYC QVSGNVMAWS EPSPLCEKIL CKPPGEIPNG KYTNSHKDVF EYNEVVTYSC LSSTGPDEFS LVGESSLFCI GKDEWSSDPP ECKVVKCPYP VVPNGEIVSG FGSKFYYKAE VVFKCNAGFT LHGRDTIVCG ANSTWEPEMP QCIKDSKPTD PPATPGPSHP GPPSPSDASP PKDAESLDG. It is sometimes possible for the material contained within the vial of "Membrane cofactor protein (CD46), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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