CD155 / PVR recombinant protein
Recombinant Mouse CD155 / PVR Protein (His tag)
Gene Names
Pvr; PVS; mE4; HVED; Taa1; CD155; Tage4; necl-5; D7Ertd458e; 3830421F03Rik
Purity
> 97 % as determined by SDS-PAGE
Synonyms
CD155 / PVR; Recombinant Mouse CD155 / PVR Protein (His tag); 3830421F03Rik; CD155; D7Ertd458e; HVED; PVS; Taa1; Tage4; mE4; CD155 / PVR recombinant protein
Host
Human Cells
Purity/Purification
> 97 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
408
Application Notes
The secreted recombinant mouse CD155 generated after removal of the signal peptide comprises 329 amino acids with a predicted molecular mass of 28 kDa. As a result of glycosylation, it migrates as an approximately 60-65 kDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Gly 28
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
Related Product Information for CD155 / PVR recombinant protein
Background: CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
Description: A DNA sequence encoding the mouse CD155 (NP_081790.1) precursor (Met 1-Arg 345) was expressed with a C-terminal polyhistidine tag.
Description: A DNA sequence encoding the mouse CD155 (NP_081790.1) precursor (Met 1-Arg 345) was expressed with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
poliovirus receptor
NCBI Official Synonym Full Names
poliovirus receptor
NCBI Official Symbol
Pvr
NCBI Official Synonym Symbols
PVS; mE4; HVED; Taa1; CD155; Tage4; necl-5; D7Ertd458e; 3830421F03Rik
NCBI Protein Information
poliovirus receptor
Research Articles on CD155 / PVR
Similar Products
Product Notes
The CD155 / PVR (Catalog #AAA2547072) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant mouse CD155 generated after removal of the signal peptide comprises 329 amino acids with a predicted molecular mass of 28 kDa. As a result of glycosylation, it migrates as an approximately 60-65 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CD155 / PVR for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD155 / PVR, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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