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Gene Sequencing (Gene Sequencing (extract))

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Recombinant Protein | MIP1a recombinant protein

Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a)

Gene Names
Ccl3; Mip1a; Scya3; G0S19-1; AI323804; MIP1-(a); LD78alpha; MIP-1alpha; MIP1-alpha
Applications
SDS-Page, Western Blot
Purity
Greater than 90% by SDS-PAGE
Synonyms
Macrophage Inflammatory Protein 1 Alpha (MIP1a); Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a); MIP1a/Macrophage Inflammatory Protein 1 Alpha; CCL3; MIP1-A; SCYA3; Chemokine C-C-Motif Ligand 3; Small Inducible Cytokine A3; Homologous To Mouse Mip-1a; Tonsillar Lymphocyte LD78 Alpha Protein; MIP1a recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 90% by SDS-PAGE
Form/Format
Freeze-dried powder
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Sequence
Ala24~Ala92
Applicable Applications for MIP1a recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Endotoxin
<1.0EU per 1ug (determined by the LAL method)
Tag
N-terminal His Tag
Expression System
Prokaryotic expression
Organism Species
Mouse
Isoelectric Point
4.9
Reconstitution
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0mg/mL. Do not vortex.
Preparation and Storage
Store at 2-8 degree C for one month, -80 degree C for 12 months
Stable for 12 months if correctly stored.
The thermal stability is described by the loss rate. The loss rate was determinedby accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and noobvious degradation and precipitation were observed. The loss rate is less than 5% within theexpiration date under appropriate storage condition.

Gene Sequencing

(Gene Sequencing (extract))

Gene Sequencing (Gene Sequencing (extract))

SDS-Page

(SDS-PAGE)

SDS-Page (SDS-PAGE)
Product Categories/Family for MIP1a recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,345 Da
NCBI Official Full Name
C-C motif chemokine 3
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 3
NCBI Official Symbol
Ccl3
NCBI Official Synonym Symbols
Mip1a; Scya3; G0S19-1; AI323804; MIP1-(a); LD78alpha; MIP-1alpha; MIP1-alpha
NCBI Protein Information
C-C motif chemokine 3; L2G25B; MIP-1 alpha; MIP-1-alpha; MIP1 (a); SIS-alpha; TY-5; heparin-binding chemotaxis protein; macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1alpha; small inducible cytokine A3; small-inducible cytokine
UniProt Protein Name
C-C motif chemokine 3
Protein Family
UniProt Gene Name
Ccl3
UniProt Synonym Gene Names
Mip1a; Scya3; MIP-1-alpha
UniProt Entry Name
CCL3_MOUSE

Uniprot Description

CCL3L1: Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1- infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Chemokine; Secreted, signal peptide

Cellular Component: extracellular space; cell; extracellular region; cytosol

Molecular Function: protein binding; chemokine activity; cytokine activity

Biological Process: neutrophil chemotaxis; positive regulation of osteoclast differentiation; leukocyte chemotaxis; positive regulation of interleukin-1 beta secretion; chemotaxis; positive regulation of tumor necrosis factor production; macrophage chemotaxis; regulation of cell shape; elevation of cytosolic calcium ion concentration; positive regulation of neuron apoptosis; immune response; positive regulation of transcription from RNA polymerase II promoter; inflammatory response; astrocyte cell migration; positive regulation of inflammatory response

Research Articles on MIP1a

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Product Notes

The MIP1a ccl3 (Catalog #AAA2125411) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Macrophage Inflammatory Protein 1 Alpha (MIP1a) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the MIP1a ccl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Ala24~Ala9 2. It is sometimes possible for the material contained within the vial of "Macrophage Inflammatory Protein 1 Alpha (MIP1a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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