Typical Testing Data/Standard Curve (for reference only)
Human Caspase-2 ELISA Kit | CASP2 elisa kit
Human Caspase-2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
may play a role in proteolysis and programmed cell death [RGD, Feb 2006]
Uniprot Description
CASP2: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD. Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle. Belongs to the peptidase C14A family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; EC 3.4.22.55; Protease
Chromosomal Location of Human Ortholog: 4q24
Cellular Component: cytoplasm; membrane; mitochondrion; nucleus
Molecular Function: cysteine-type endopeptidase activity; identical protein binding; protein binding; protein domain specific binding
Biological Process: aging; apoptosis; brain development; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; germ cell programmed cell death; luteolysis; positive regulation of apoptosis; positive regulation of neuron apoptotic process; programmed cell death; protein processing; proteolysis; regulation of apoptosis
Research Articles on CASP2
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Product Notes
The Human CASP2 casp2 (Catalog #AAA2888242) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2888242 ELISA Kit recognizes Human CASP2. It is sometimes possible for the material contained within the vial of "Caspase-2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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