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Calcium Channel, Voltage Dependent, T-Type, Alpha 1H Subunit Recombinant Protein | CACNa1H recombinant protein
Recombinant Calcium Channel, Voltage Dependent, T-Type, Alpha 1H Subunit (CACNa1H)
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
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SDS-Page
NCBI and Uniprot Product Information
NCBI Description
acts as a low voltage gated calcium channel; conducts calcium current; involved in neuronal physiology [RGD, Feb 2006]
Uniprot Description
CACNA1H: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1H gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell development/differentiation; Channel, calcium
Research Articles on CACNa1H
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Product Notes
The CACNa1H cacna1h (Catalog #AAA2033518) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Calcium Channel, Voltage Dependent, T-Type, Alpha 1H Subunit can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CACNa1H cacna1h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: S VELDNGDGHL ESGEVRARAS ELEPALGARR KKKMSPPCIS IDPPTEDEGS SRPPAAEGGN TTLRRRTPSC EAALHRDCPE STEGPGTGGD PVAKGERWGQ ASCRAEHLTV PNFAFEPLDM GGPGGDCFLD SDQSVTPEPR VSSLGAIVPL ILETELSMPS GDPPEKEQGL YLTVPQTPLK KPGSPPATPA PDDSGDEPV. It is sometimes possible for the material contained within the vial of "Calcium Channel, Voltage Dependent, T-Type, Alpha 1H Subunit, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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