Typical Testing Data/Standard Curve (for reference only)
Rat Carbonic anhydrase 4 ELISA Kit | Ca4 elisa kit
Rat Carbonic anhydrase 4 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
may be involved in carbon dioxide exchange and pH reguation [RGD, Feb 2006]
Uniprot Description
CA4: Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid. Defects in CA4 are the cause of retinitis pigmentosa type 17 (RP17). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP17 inheritance is autosomal dominant. Defective acid overload removal from retina and retinal epithelium, due to mutant CA4, is responsible for photoreceptor degeneration, indicating that impaired pH homeostasis is the most likely cause underlying the RP17 phenotype. Belongs to the alpha-carbonic anhydrase family.
Protein type: Membrane protein, anchored; Endoplasmic reticulum; Cell surface; Lyase; Vesicle; EC 4.2.1.1; Energy Metabolism - nitrogen; Membrane protein, GPI anchor
Cellular Component: anchored to external side of plasma membrane; anchored to plasma membrane; apical plasma membrane; basolateral plasma membrane; brush border membrane; cell surface; ER-Golgi intermediate compartment; Golgi apparatus; membrane; perinuclear region of cytoplasm; plasma membrane; rough endoplasmic reticulum; sarcolemma; sarcoplasmic reticulum; secretory granule membrane; trans-Golgi network
Molecular Function: carbonate dehydratase activity; zinc ion binding
Biological Process: bicarbonate transport; one-carbon compound metabolic process; organ development; response to drug; response to steroid hormone stimulus
Research Articles on Ca4
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Product Notes
The Rat Ca4 ca4 (Catalog #AAA2886456) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886456 ELISA Kit recognizes Rat Ca4. It is sometimes possible for the material contained within the vial of "Carbonic anhydrase 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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