Human Complement Fragment 3B Rccptor ELISA Kit | C3BR elisa kit

Human Complement Fragment 3B Rccptor ELISA Kit

Cat. Num. AAA12002

• Gene Names: Cr1l; Cr1; Crry
• Reactivity: Human
• Synonyms: Complement Fragment 3B Rccptor; Human Complement Fragment 3B Rccptor ELISA Kit; C3BR elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.
• Sequence Length: 621

• Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
• Assay Type: Sandwich
• Detection Range: 31.2 ng/ml - 1000 ng/ml.
• Sensitivity: 5.0ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for C3BR elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of C3BR (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 53759110
• NCBI GeneID: 54243
• NCBI Accession #: NP_001005330.1
• NCBI GenBank Nucleotide #: NM_001005330.1
• UniProt Accession #: Q63135; Q63612
• Molecular Weight: 61,680 Da
• NCBI Official Full Name: complement component receptor 1-like protein isoform 1
• NCBI Official Synonym Full Names: complement component (3b/4b) receptor 1-like
• NCBI Official Symbol: Cr1l
• NCBI Official Synonym Symbols: Cr1; Crry
• NCBI Protein Information: complement component receptor 1-like protein; 5I2 antigen; antigen 5I2; complement receptor type 1; complement regulatory protein Crry; Complement receptor related protein
• UniProt Protein Name: Complement component receptor 1-like protein
• UniProt Gene Name: Cr1l
• UniProt Synonym Gene Names: Crry
• UniProt Entry Name: CR1L_RAT

NCBI Description

This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Crry: Belongs to the receptors of complement activation (RCA) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Membrane protein, integral; Secreted

Cellular Component: integral to membrane; receptor complex; external side of plasma membrane

Biological Process: in utero embryonic development; negative regulation of complement activation; multicellular organismal development; regulation of complement activation; innate immune response; female pregnancy; complement activation, classical pathway