Rabbit anti-Human ASMTL Polyclonal Antibody | anti-ASMTL antibody

ASMTL (N-acetylserotonin O-methyltransferase-like Protein)

Cat. Num. AAA649370

• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ASMTL; Polyclonal Antibody; ASMTL (N-acetylserotonin O-methyltransferase-like Protein); Anti -ASMTL (N-acetylserotonin O-methyltransferase-like Protein); anti-ASMTL antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ASMTL.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSKVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP

• Applicable Applications for anti-ASMTL antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human ASMTL, aa1-621 (AAH02508.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ASMTL rabbit polyclonal antibody. Western Blot analysis of ASMTL expression in human liver.)

Western Blot (WB)

(Western Blot analysis of ASMTL expression in transfected 293T cell line by ASMTL polyclonal antibody. Lane 1: ASMTL transfected lysate (68.8kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-ASMTL antibody

Antibodies; Abs to Enzymes; Methyltransferase

NCBI and Uniprot Product Information

• NCBI GI #: 3808149
• UniProt Accession #: O95671; Q5JQ53; Q8NBH5; Q96G02; Q9BUL6; B4DX75; F5GXH4; J3JS33
• Molecular Weight: 68,857 Da
• NCBI Official Full Name: ASMTL
• UniProt Protein Name: N-acetylserotonin O-methyltransferase-like protein
• Protein Family: N-acetylserotonin O-methyltransferase-like protein
• UniProt Gene Name: ASMTL
• UniProt Synonym Gene Names: ASMTL
• UniProt Entry Name: ASML_HUMAN

Uniprot Description

Function: Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity.

Tissue specificity: Widely expressed. In adult, highly expressed in pancreas, placenta, fibroblast, thymus, prostate, testis, ovary and colon. Expressed at lower levels in spleen, small intestine and leukocytes. In fetus, expressed at high levels in the lung and kidney and at lower level in brain and liver.

Miscellaneous: The gene coding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It represents a unique fusion product of 2 different genes of different evolutionary origin and function. The N-terminus is homologous to the bacterial maf/orfE genes and the C-terminus is homologous to ASMT. Exon duplication, exon shuffling and gene fusion seem to be common characteristics of the PAR1 region.

Sequence similarities: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.In the N-terminal section; belongs to the maf family.

Sequence caution: The sequence CAA75675.1 differs from that shown. Reason: Frameshift at position 616. The sequence CAA75676.1 differs from that shown. Reason: Frameshift at position 616.