Human chromosome 15 open reading frame 42 ELISA Kit | C15orf42 elisa kit
Human Treslin, C15orf42 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010]
Uniprot Description
TICRR: Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre- initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. Belongs to the treslin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA replication; Cell cycle regulation
Chromosomal Location of Human Ortholog: 15q26.1
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; chromatin binding
Biological Process: regulation of DNA replication initiation; mitotic cell cycle DNA replication checkpoint; response to ionizing radiation; DNA replication; DNA repair; cell cycle checkpoint; formation of translation preinitiation complex
Research Articles on C15orf42
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Product Notes
The Human C15orf42 ticrr (Catalog #AAA9330907) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330907 ELISA Kit recognizes Human C15orf42. It is sometimes possible for the material contained within the vial of "chromosome 15 open reading frame 42, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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