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Immunohistochemistry (IHC) ((1ug/ml) staining of Pig Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

PTGR2/ZADH1 Antibody | anti-PTGR2 antibody

Goat anti-PTGR2/ZADH1 Antibody

Gene Names
PTGR2; PGR2; ZADH1; HEL-S-298
Reactivity
Pig
Expected from sequence similarity: Human
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
PTGR2/ZADH1; Goat anti-PTGR2/ZADH1 Antibody; PTGR2; prostaglandin reductase 2; PGR2; ZADH1; 15-oxoprostaglandin 13-reductase; 15-oxoprostaglandin-delta13-reductase; PRG-2; zinc binding alcohol dehydrogenase; domain containing 1; zinc-binding alcohol dehydrogenase domain-containing protein 1; anti-PTGR2 antibody
Ordering
For Research Use Only!
Reactivity
Pig
Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Sequence Length
351
Applicable Applications for anti-PTGR2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Pep-ELISA: antibody detection limit dilution 1:128000.
WB: Approx 38kDa band observed in Pig Testis lysates. Recommended concentration: 1-3ug/ml.
Immunogen Sequence
Peptide with sequence C-PDNINEGQVQVRT, from the internal region (near N terminus) of the protein sequence according to NP_689657.1.
Peptide Sequence + C
C-PDNINEGQVQVRT
Epitope
Internal Region (near N terminus)
Note
Reported variants represent identical protein: NP_001139627.1, NP_689657.1, NP_001139626.1.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

((1ug/ml) staining of Pig Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Immunohistochemistry (IHC) ((1ug/ml) staining of Pig Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38.4kDa
NCBI Official Full Name
prostaglandin reductase 2
NCBI Official Synonym Full Names
prostaglandin reductase 2
NCBI Official Symbol
PTGR2
NCBI Official Synonym Symbols
PGR2; ZADH1; HEL-S-298
NCBI Protein Information
prostaglandin reductase 2
UniProt Protein Name
Prostaglandin reductase 2
Protein Family
UniProt Gene Name
PTGR2
UniProt Synonym Gene Names
ZADH1; PRG-2

NCBI Description

This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Uniprot Description

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation ().

Research Articles on PTGR2

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Product Notes

The PTGR2 ptgr2 (Catalog #AAA423798) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-PTGR2/ZADH1 Antibody reacts with Pig Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTGR2/ZADH1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Pep-ELISA: antibody detection limit dilution 1:128000. WB: Approx 38kDa band observed in Pig Testis lysates. Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the PTGR2 ptgr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGR2/ZADH1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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