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ZACN blocking peptide

ZACN Antibody (C-term) Blocking Peptide

Gene Names
ZACN; L2; ZAC; ZAC1; LGICZ; LGICZ1
Synonyms
ZACN; ZACN Antibody (C-term) Blocking Peptide; Zinc-activated ligand-gated ion channel; Ligand-gated ion channel zinc-activated 1; Ligand-gated ion-channel receptor L2; L2; LGICZ; LGICZ1; ZAC; ZACN blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
412
Cellular Location
Cell membrane; Multi-pass membrane protein
Tissue Location
Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ZACN blocking peptide
Zinc-activated ligand-gated ion channel.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
13,299 Da
NCBI Official Full Name
Zinc-activated ligand-gated ion channel
NCBI Official Synonym Full Names
zinc activated ion channel
NCBI Official Symbol
ZACN
NCBI Official Synonym Symbols
L2; ZAC; ZAC1; LGICZ; LGICZ1
NCBI Protein Information
zinc-activated ligand-gated ion channel
UniProt Protein Name
Zinc-activated ligand-gated ion channel
UniProt Gene Name
ZACN
UniProt Synonym Gene Names
L2; LGICZ; LGICZ1; ZAC
UniProt Entry Name
ZACN_HUMAN

NCBI Description

LGICZ1 is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels (Davies et al., 2003 [PubMed 12381728]).[supplied by OMIM, Mar 2008]

Uniprot Description

ZACN: Zinc-activated ligand-gated ion channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: nicotinic acetylcholine-gated receptor-channel complex; plasma membrane

Molecular Function: acetylcholine binding; acetylcholine receptor activity; ligand-gated ion channel activity; nicotinic acetylcholine-activated cation-selective channel activity; serotonin receptor activity; serotonin-activated cation-selective channel activity; zinc ion binding

Biological Process: response to zinc ion; serotonin receptor signaling pathway; synaptic transmission, cholinergic

Research Articles on ZACN

Similar Products

Product Notes

The ZACN zacn (Catalog #AAA9225511) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZACN, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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