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WDR1 blocking peptide

WDR1 Antibody (C-term) Blocking Peptide

Gene Names
WDR1; AIP1; NORI-1; HEL-S-52
Synonyms
WDR1; WDR1 Antibody (C-term) Blocking Peptide; WD repeat-containing protein 1; Actin-interacting protein 1; AIP1; NORI-1; WDR1 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human WDR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
606
Cellular Location
Cytoplasm, cytoskeleton. Cell projection, podosome
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for WDR1 blocking peptide
Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
50,694 Da
NCBI Official Full Name
WD repeat-containing protein 1
NCBI Official Synonym Full Names
WD repeat domain 1
NCBI Official Symbol
WDR1
NCBI Official Synonym Symbols
AIP1; NORI-1; HEL-S-52
NCBI Protein Information
WD repeat-containing protein 1
UniProt Protein Name
WD repeat-containing protein 1
UniProt Gene Name
WDR1
UniProt Synonym Gene Names
AIP1
UniProt Entry Name
WDR1_HUMAN

NCBI Description

This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

WDR1: a WD40 repeat cytoskeletal protein that induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: cytoplasm; cytosol; extracellular region

Biological Process: platelet degranulation; sensory perception of sound

Research Articles on WDR1

Similar Products

Product Notes

The WDR1 wdr1 (Catalog #AAA9224944) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "WDR1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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