TSNAX blocking peptide

TSNAX Antibody (N-term) Blocking peptide

• Gene Names: TSNAX; TRAX
• Synonyms: TSNAX; TSNAX Antibody (N-term) Blocking peptide; Translin-associated protein X; Translin-associated factor X; TRAX; TSNAX blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the N-term region of TSNAX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 290

• Cellular Location: Cytoplasm, perinuclear region. Golgi apparatus. Nucleus. Note: Accumulate in the Golgi complex of mid-late pachytene spermatocytes (By similarity) Expressed in the cytoplasm in the presence of TSN.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TSNAX blocking peptide

Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis.

NCBI and Uniprot Product Information

• NCBI GI #: 6136057
• NCBI GeneID: 7257
• UniProt Accession #: Q99598; B1APC6
• Molecular Weight: 33,112 Da
• NCBI Official Full Name: Translin-associated protein X
• NCBI Official Synonym Full Names: translin associated factor X
• NCBI Official Symbol: TSNAX
• NCBI Official Synonym Symbols: TRAX
• NCBI Protein Information: translin-associated protein X
• UniProt Protein Name: Translin-associated protein X
• Protein Family: Translin-associated protein
• UniProt Gene Name: TSNAX
• UniProt Synonym Gene Names: TRAX
• UniProt Entry Name: TSNAX_HUMAN

NCBI Description

This gene encodes a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. The encoded protein contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks any nuclear targeting motifs. [provided by RefSeq, Jul 2008]

Uniprot Description

TSNAX: Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis. Belongs to the translin family.

Protein type: Nuclear receptor co-regulator; DNA-binding

Chromosomal Location of Human Ortholog: 1q42.1

Cellular Component: cytosol; nucleus

Molecular Function: DNA binding; protein binding; protein transporter activity

Biological Process: RNA-mediated gene silencing