TMEM100 blocking peptide
TMEM100 Antibody (C-term) Blocking peptide
Synonyms
TMEM100; TMEM100 Antibody (C-term) Blocking peptide; Transmembrane protein 100; TMEM100 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
134
Cellular Location
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein Perikaryon. Cytoplasm, perinuclear region. Endoplasmic reticulum Note: Colocalized with HSPA5 in the endoplasmic reticulum (ER) Enriched in ER microsome. Colocalized with BMP4 in neural cell bodies and neural fibers of the enteric nervous system
Tissue Location
Expressed in neurons of the myenteric and submucosal plexuses in the gastric body, jejunum and proximal colon. Expressed in arterial endothelial cells and neurons of the central nervous system and peripheral nervous system. Expressed in umbilical artery endothelial cells (at protein level)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TMEM100 blocking peptide
Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,386 Da
NCBI Official Full Name
transmembrane protein 100
NCBI Official Synonym Full Names
transmembrane protein 100
NCBI Official Symbol
TMEM100
NCBI Protein Information
transmembrane protein 100
UniProt Protein Name
Transmembrane protein 100
Protein Family
UniProt Gene Name
TMEM100
UniProt Entry Name
TM100_HUMAN
Uniprot Description
TMEM100: Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Up-regulated by GDF2/BMP9 and BMP10 (at protein level)
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17q22
Cellular Component: endoplasmic reticulum; perikaryon; perinuclear region of cytoplasm; plasma membrane
Molecular Function: protein binding
Biological Process: BMP signaling pathway; positive regulation of endothelial cell differentiation; regulation of sensory perception of pain
Research Articles on TMEM100
Similar Products
Product Notes
The TMEM100 tmem100 (Catalog #AAA9218582) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TMEM100, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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