TLE1 blocking peptide
TLE1 Blocking Peptide (N-term)
Gene Names
TLE1; ESG; ESG1; GRG1
Synonyms
TLE1; TLE1 Blocking Peptide (N-term); Transducin-like enhancer protein 1; E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1; TLE1 blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 187-201 of HUMAN TLE1
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
770
Cellular Location
Nucleus. Note: Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components
Tissue Location
In all tissues examined, mostly in brain, liver and muscle
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TLE1 blocking peptide
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
83,201 Da
NCBI Official Full Name
Transducin-like enhancer protein 1
NCBI Official Synonym Full Names
transducin like enhancer of split 1
NCBI Official Symbol
TLE1
NCBI Official Synonym Symbols
ESG; ESG1; GRG1
NCBI Protein Information
transducin-like enhancer protein 1
UniProt Protein Name
Transducin-like enhancer protein 1
Protein Family
UniProt Gene Name
TLE1
UniProt Synonym Gene Names
ESG1
UniProt Entry Name
TLE1_HUMAN
Uniprot Description
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Research Articles on TLE1
Similar Products
Product Notes
The TLE1 tle1 (Catalog #AAA9229662) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TLE1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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