TAS1R3 blocking peptide

TAS1R3 Blocking Peptide

Cat. Num. AAA9625338

• Gene Names: TAS1R3; T1R3
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: TAS1R3; TAS1R3 Blocking Peptide; G protein coupled receptor; Sac; Saccharin preference; Sweet taste receptor T1R3; T1 R3; T1R 3; T1R3; TAS1 R3; TAS1R 3; Taste receptor type 1 member 3; Taste receptor type 1 member 3 precursor; TR 3; TR3; TS1R3_HUMAN; TAS1R3 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for TAS1R3 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TAS1R3 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 91206396
• NCBI GeneID: 83756
• NCBI Accession #: NP_689414.1
• NCBI GenBank Nucleotide #: NM_152228.2
• UniProt Accession #: Q7RTX0; Q5TA49; Q8NGW9
• Molecular Weight: 93,386 Da
• NCBI Official Full Name: taste receptor type 1 member 3
• NCBI Official Synonym Full Names: taste receptor, type 1, member 3
• NCBI Official Symbol: TAS1R3
• NCBI Official Synonym Symbols: T1R3
• NCBI Protein Information: taste receptor type 1 member 3; sweet taste receptor T1R3
• UniProt Protein Name: Taste receptor type 1 member 3
• Protein Family: Taste receptor
• UniProt Gene Name: TAS1R3
• UniProt Synonym Gene Names: T1R3; TR3
• UniProt Entry Name: TS1R3_HUMAN

NCBI Description

The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 [PubMed 11326277]).[supplied by OMIM, Jan 2010]

Uniprot Description

TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.

Protein type: GPCR, family 3; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.33

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein heterodimerization activity; sweet taste receptor activity; taste receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; sensory perception of umami taste; sensory perception of sweet taste; detection of chemical stimulus involved in sensory perception of sweet taste