TAF1D blocking peptide

TAF1D Antibody (N-term) Blocking peptide

• Gene Names: TAF1D; JOSD3; RAFI41; TAFI41; TAF(I)41
• Synonyms: TAF1D; TAF1D Antibody (N-term) Blocking peptide; TATA box-binding protein-associated factor RNA polymerase I subunit D; RNA polymerase I-specific TBP-associated factor 41 kDa; TAFI41; TATA box-binding protein-associated factor 1D; TBP-associated factor 1D; Transcription initiation factor SL1/TIF-IB subunit D; JOSD3; TAF1D blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 278

• Cellular Location: Nucleus
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TAF1D blocking peptide

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.

NCBI and Uniprot Product Information

• NCBI GI #: 13129136
• NCBI GeneID: 79101
• NCBI Accession #: NP_077021.1
• NCBI GenBank Nucleotide #: NM_024116.3
• UniProt Accession #: Q9H5J8; Q6I9Y6
• Molecular Weight: 32,058 Da
• NCBI Official Full Name: TATA box-binding protein-associated factor RNA polymerase I subunit D
• NCBI Official Synonym Full Names: TATA-box binding protein associated factor, RNA polymerase I subunit D
• NCBI Official Symbol: TAF1D
• NCBI Official Synonym Symbols: JOSD3; RAFI41; TAFI41; TAF(I)41
• NCBI Protein Information: TATA box-binding protein-associated factor RNA polymerase I subunit D
• UniProt Protein Name: TATA box-binding protein-associated factor RNA polymerase I subunit D
• Protein Family: TATA box-binding protein-associated factor
• UniProt Gene Name: TAF1D
• UniProt Synonym Gene Names: JOSD3; TAFI41; TBP-associated factor 1D
• UniProt Entry Name: TAF1D_HUMAN

NCBI Description

TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).[supplied by OMIM, Jun 2009]

Uniprot Description

TAF1D: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: microtubule organizing center; nucleoplasm

Molecular Function: protein binding

Biological Process: positive regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter