SLC6A14 blocking peptide

SLC6A14 Blocking Peptide

Cat. Num. AAA9628944

• Gene Names: SLC6A14; BMIQ11
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: SLC6A14; SLC6A14 Blocking Peptide; Amino acid transporter ATB0+; Amino acid transporter B0+; ATB0+; BMIQ11; OBX; Sodium and chloride dependent neutral and basic amino acid transporter B(0+); Sodium and chloride dependent neutral and basic amino acid transporter B0+; Solute carrier family 6 (amino acid transporter); member 14; Solute carrier family 6 (neurotransmitter transporter); Solute carrier family 6 amino acid transporter member 14; Solute carrier family 6 member 14; Solute carrier family 6 neurotransmitter transporter member 14; SLC6A14 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for SLC6A14 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SLC6A14 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 6005715
• NCBI GeneID: 11254
• NCBI Accession #: NP_009162.1
• NCBI GenBank Nucleotide #: NM_007231.4
• UniProt Accession #: Q9UN76; Q5H942
• Molecular Weight: 72,153 Da
• NCBI Official Full Name: sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
• NCBI Official Synonym Full Names: solute carrier family 6 (amino acid transporter), member 14
• NCBI Official Symbol: SLC6A14
• NCBI Official Synonym Symbols: BMIQ11
• NCBI Protein Information: sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); amino acid transporter B0+; amino acid transporter ATB0+; solute carrier family 6 (neurotransmitt
• UniProt Protein Name: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
• Protein Family: Sodium- and chloride-dependent neutral and basic amino acid transporter
• UniProt Gene Name: SLC6A14
• UniProt Entry Name: S6A14_HUMAN

NCBI Description

This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010]

Uniprot Description

SLC6A14: Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by significant differences in allele frequencies between obese and non-obese individuals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq23

Cellular Component: brush border membrane; integral to membrane; plasma membrane; vesicle

Molecular Function: neurotransmitter:sodium symporter activity; amino acid transmembrane transporter activity

Biological Process: amino acid metabolic process; amino acid transport; neurotransmitter transport; transport; response to toxin; ion transport; transmembrane transport

Disease: Body Mass Index Quantitative Trait Locus 11