SLC43A2 blocking peptide

SLC43A2 Antibody (Center) Blocking peptide

• Gene Names: SLC43A2; LAT4
• Synonyms: SLC43A2; SLC43A2 Antibody (Center) Blocking peptide; Large neutral amino acids transporter small subunit 4; L-type amino acid transporter 4; Solute carrier family 43 member 2; LAT4; SLC43A2 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 569

• Cellular Location: Membrane; Multi-pass membrane protein
• Tissue Location: Detected in several tissues with higher expression in placenta, kidney and peripheral blood leukocytes. In the kidney, is detected in epithelial cells of the distal tubule and collecting duct. In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for SLC43A2 blocking peptide

Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids.

NCBI and Uniprot Product Information

• NCBI GI #: 22748751
• NCBI GeneID: 124935
• NCBI Accession #: NP_689559.1
• NCBI GenBank Nucleotide #: NM_152346.2
• UniProt Accession #: Q8N370; Q5CD75; Q6IPM1; Q8NBX1; Q8NC21; Q8WZ00; B7Z6X9; C9JNU8; D3DTH9
• Molecular Weight: 47,968 Da
• NCBI Official Full Name: large neutral amino acids transporter small subunit 4 isoform 2
• NCBI Official Synonym Full Names: solute carrier family 43 member 2
• NCBI Official Symbol: SLC43A2
• NCBI Official Synonym Symbols: LAT4
• NCBI Protein Information: large neutral amino acids transporter small subunit 4
• UniProt Protein Name: Large neutral amino acids transporter small subunit 4
• Protein Family: Large neutral amino acids transporter
• UniProt Gene Name: SLC43A2
• UniProt Synonym Gene Names: LAT4
• UniProt Entry Name: LAT4_HUMAN

NCBI Description

This gene encodes a member of the L-amino acid transporter-3 or SLC43 family of transporters. The encoded protein mediates sodium-, chloride-, and pH-independent transport of L-isomers of neutral amino acids, including leucine, phenylalanine, valine and methionine. This protein may contribute to the transfer of amino acids across the placental membrane to the fetus. [provided by RefSeq, Mar 2016]

Uniprot Description

SLC43A2: Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. Belongs to the SLC43A transporter (TC 2.A.1.44) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: amino acid transmembrane transporter activity; L-amino acid transmembrane transporter activity; neutral amino acid transmembrane transporter activity

Biological Process: amino acid transport