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SEC23IP blocking peptide

SEC23IP Antibody (C-term) Blocking Peptide

Gene Names
SEC23IP; P125; P125A; MSTP053
Synonyms
SEC23IP; SEC23IP Antibody (C-term) Blocking Peptide; SEC23-interacting protein; p125; SEC23IP blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
1000
Cellular Location
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Endoplasmic reticulum
Tissue Location
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SEC23IP blocking peptide
Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
102,187 Da
NCBI Official Full Name
SEC23-interacting protein
NCBI Official Synonym Full Names
SEC23 interacting protein
NCBI Official Symbol
SEC23IP
NCBI Official Synonym Symbols
P125; P125A; MSTP053
NCBI Protein Information
SEC23-interacting protein
UniProt Protein Name
SEC23-interacting protein
Protein Family
UniProt Gene Name
SEC23IP
UniProt Entry Name
S23IP_HUMAN

NCBI Description

This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Uniprot Description

SEC23IP: Plays a role in the organization of endoplasmic reticulum exit sites. Belongs to the PA-PLA1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10q25-q26

Cellular Component: cytoplasm; cytosol; ER to Golgi transport vesicle; ER-Golgi intermediate compartment

Molecular Function: protein binding

Biological Process: COPII coating of Golgi vesicle; Golgi organization and biogenesis; intracellular protein transport

Research Articles on SEC23IP

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Product Notes

The SEC23IP sec23ip (Catalog #AAA9220849) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SEC23IP, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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