Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Scx blocking peptide

Scx Blocking Peptide (C-term)

Gene Names
Scx; Scl; Bhlha41; BB114693
Synonyms
Scx; Scx Blocking Peptide (C-term); Basic helix-loop-helix transcription factor scleraxis; Scx blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 172-185 of HUMAN Scx
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
207
Cellular Location
Nucleus
Tissue Location
Expressed in mesenchymal precursors of cartilage and in connective tissue. Highly expressed in tendons in the limb, tongue and diaphragm and in cartilage of the bronchi
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Scx blocking peptide
Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22,239 Da
NCBI Official Full Name
Basic helix-loop-helix transcription factor scleraxis
NCBI Official Synonym Full Names
scleraxis
NCBI Official Symbol
Scx
NCBI Official Synonym Symbols
Scl; Bhlha41; BB114693
NCBI Protein Information
basic helix-loop-helix transcription factor scleraxis
UniProt Protein Name
Basic helix-loop-helix transcription factor scleraxis
UniProt Gene Name
Scx
UniProt Entry Name
SCX_MOUSE

NCBI Description

This gene encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. The encoded protein is expressed during embryonic development of tendons and ligaments. The gene product regulates collagen type I gene expression in cardiac fibroblasts and myofibroblasts, and it may play a role in myocardial remodeling. The protein is expressed in the scar area of the adult heart following myocardial infarction. [provided by RefSeq, Feb 2010]

Uniprot Description

SCXA: Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.

Protein type: DNA-binding; Transcription regulation

Cellular Component: nucleus; transcription factor complex

Molecular Function: bHLH transcription factor binding; DNA binding; protein binding; protein heterodimerization activity; sequence-specific DNA binding

Biological Process: BMP signaling pathway; cell differentiation; chondrocyte differentiation; collagen fibril organization; endochondral ossification; mesoderm formation; negative regulation of apoptosis; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; tissue homeostasis; transcription, DNA-dependent

Research Articles on Scx

Similar Products

Product Notes

The Scx scx (Catalog #AAA9229930) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Scx, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.