RWDD3 blocking peptide

RWDD3 Peptide

Cat. Num. AAA151978

• Gene Names: RWDD3; RSUME
• Applications: Blocking (BL)
• Synonyms: RWDD3; RWDD3 Peptide; RSUME; RWD domain-containing protein 3; RWD-containing sumoylation enhancer; RWD domain containing 3; RWDD3 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 267

• Applicable Applications for RWDD3 blocking peptide: Blocking (BL)
• Application Notes: RWDD3 peptide is used for blocking the activity of RWDD3 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 15 amino acids near the carboxy terminus of human RWDD3.
• Preparation and Storage: Store RWDD3 peptide at -20 degree C, stable for one year.

Western Blot (WB)

(Western blot analysis of RWDD3 in rat kidney tissue lysate with RWDD3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 153252154
• NCBI GeneID: 25950
• NCBI Accession #: NP_056300
• NCBI GenBank Nucleotide #: NM_015485.4
• UniProt Accession #: Q9Y3V2; Q08AJ7; Q6FID3; Q9BX35; A6NP44; A8K9F0; C9J9L7; C9JI45
• Molecular Weight: 22,857 Da
• NCBI Official Full Name: RWD domain-containing protein 3 isoform a
• NCBI Official Synonym Full Names: RWD domain containing 3
• NCBI Official Symbol: RWDD3
• NCBI Official Synonym Symbols: RSUME
• NCBI Protein Information: RWD domain-containing protein 3; RWD-containing sumoylation enhancer; RWD domain-containing sumoylation enhancer
• UniProt Protein Name: RWD domain-containing protein 3
• Protein Family: RWD domain-containing protein
• UniProt Gene Name: RWDD3
• UniProt Synonym Gene Names: RSUME; RSUME
• UniProt Entry Name: RWDD3_HUMAN

Uniprot Description

RWDD3: Enhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: SUMO conjugating system

Chromosomal Location of Human Ortholog: 1p21.3

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: positive regulation of protein sumoylation; inhibition of NF-kappaB transcription factor