RPAP2 blocking peptide
RPAP2 Blocking Peptide
Gene Names
RPAP2; C1orf82
Applications
Blocking/Control
Purity
The purity is >90%,tested by HPLC and MS.
Synonyms
RPAP2; RPAP2 Blocking Peptide; Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; RNA polymerase II-associated protein 2; RPAP2_HUMAN; RPAP2 blocking peptide
Purity/Purification
The purity is >90%,tested by HPLC and MS.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.
Applicable Applications for RPAP2 blocking peptide
Blocking/Control
Notes
For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for RPAP2 blocking peptide
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,509 Da
NCBI Official Full Name
putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
NCBI Official Synonym Full Names
RNA polymerase II associated protein 2
NCBI Official Symbol
RPAP2
NCBI Official Synonym Symbols
C1orf82
NCBI Protein Information
putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; RNA polymerase II-associated protein 2
UniProt Protein Name
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
Protein Family
UniProt Gene Name
RPAP2
UniProt Synonym Gene Names
C1orf82
UniProt Entry Name
RPAP2_HUMAN
Uniprot Description
RPAP2: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes. Belongs to the RPAP2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.16; Membrane protein, integral; Protein phosphatase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 1p22.1
Cellular Component: cytoplasm; nucleolus; DNA-directed RNA polymerase II, holoenzyme; nucleus
Molecular Function: metal ion binding; CTD phosphatase activity
Biological Process: snRNA transcription
Research Articles on RPAP2
Similar Products
Product Notes
The RPAP2 rpap2 (Catalog #AAA9624616) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RPAP2 can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the RPAP2 rpap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RPAP2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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