RHOJ blocking peptide

RHOJ Antibody (Center) Blocking peptide

• Gene Names: RHOJ; TCL; ARHJ; TC10B; RASL7B
• Synonyms: RHOJ; RHOJ Antibody (Center) Blocking peptide; Rho-related GTP-binding protein RhoJ; Ras-like protein family member 7B; Tc10-like GTP-binding protein; ARHJ; RASL7B; RHOI; TCL; RHOJ blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 214

• Cellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for RHOJ blocking peptide

GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 16903164
• NCBI GeneID: 57381
• NCBI Accession #: NP_065714.1
• NCBI GenBank Nucleotide #: NM_020663.4
• UniProt Accession #: Q9H4E5; Q96KC1
• Molecular Weight: 21,255 Da
• NCBI Official Full Name: rho-related GTP-binding protein RhoJ
• NCBI Official Synonym Full Names: ras homolog family member J
• NCBI Official Symbol: RHOJ
• NCBI Official Synonym Symbols: TCL; ARHJ; TC10B; RASL7B
• NCBI Protein Information: rho-related GTP-binding protein RhoJ
• UniProt Protein Name: Rho-related GTP-binding protein RhoJ
• Protein Family: Rho-related GTP-binding protein
• UniProt Gene Name: RHOJ
• UniProt Synonym Gene Names: ARHJ; RASL7B; RHOI; TCL
• UniProt Entry Name: RHOJ_HUMAN

NCBI Description

This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011]

Uniprot Description

RHOJ: GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology. Belongs to the small GTPase superfamily. Rho family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric, Rho; G protein, monomeric; Motility/polarity/chemotaxis; G protein

Chromosomal Location of Human Ortholog: 14q23.2

Cellular Component: cytosol; plasma membrane

Molecular Function: protein binding

Biological Process: actin cytoskeleton organization and biogenesis; regulation of small GTPase mediated signal transduction