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RELT blocking peptide

RELT Antibody (C-term) Blocking Peptide

Gene Names
RELT; TRLT; TNFRSF19L
Synonyms
RELT; RELT Antibody (C-term) Blocking Peptide; Tumor necrosis factor receptor superfamily member 19L; Receptor expressed in lymphoid tissues; TNFRSF19L; RELT blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
430
Cellular Location
Cell membrane; Single-pass type I membrane protein Cytoplasm
Tissue Location
Highest levels are in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver Very low levels in skeletal muscle, testis and colon. Not detected in brain, kidney and pancreas.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for RELT blocking peptide
Mediates activation of NF-kappa-B. May play a role in T- cell activation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
46,092 Da
NCBI Official Full Name
Tumor necrosis factor receptor superfamily member 19L
NCBI Official Synonym Full Names
RELT tumor necrosis factor receptor
NCBI Official Symbol
RELT
NCBI Official Synonym Symbols
TRLT; TNFRSF19L
NCBI Protein Information
tumor necrosis factor receptor superfamily member 19L
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 19L
Protein Family
UniProt Gene Name
RELT
UniProt Synonym Gene Names
TNFRSF19L
UniProt Entry Name
TR19L_HUMAN

NCBI Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

RELT: Mediates activation of NF-kappa-B. May play a role in T- cell activation. Belongs to the RELT family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13.4

Cellular Component: integral to plasma membrane

Molecular Function: tumor necrosis factor receptor activity

Biological Process: immune response; inflammatory response; multicellular organismal development; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide

Research Articles on RELT

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Product Notes

The RELT relt (Catalog #AAA9222711) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RELT, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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