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PPEF2 blocking peptide

PPEF2 Antibody (Center) Blocking Peptide

Gene Names
PPEF2; PPP7CB
Synonyms
PPEF2; PPEF2 Antibody (Center) Blocking Peptide; Serine/threonine-protein phosphatase with EF-hands 2; PPEF-2; PPEF2 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
753
Cellular Location
Cytoplasm. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment Note: Localized to photoreceptors, PPEF-2(L) is at least 2 fold more abundant in rod inner segments than in the outer segments
Tissue Location
Retinal specific.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PPEF2 blocking peptide
May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
69,015 Da
NCBI Official Full Name
Serine/threonine-protein phosphatase with EF-hands 2
NCBI Official Synonym Full Names
protein phosphatase with EF-hand domain 2
NCBI Official Symbol
PPEF2
NCBI Official Synonym Symbols
PPP7CB
NCBI Protein Information
serine/threonine-protein phosphatase with EF-hands 2
UniProt Protein Name
Serine/threonine-protein phosphatase with EF-hands 2
UniProt Gene Name
PPEF2
UniProt Synonym Gene Names
PPEF-2
UniProt Entry Name
PPE2_HUMAN

NCBI Description

This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. [provided by RefSeq, Jul 2008]

Uniprot Description

PPEF2: May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission. Belongs to the PPP phosphatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 4q21.1

Molecular Function: Hsp70 protein binding; Hsp90 protein binding; mitogen-activated protein kinase kinase kinase binding; protein binding; protein serine/threonine phosphatase activity

Biological Process: negative regulation of MAPKKK cascade; protein amino acid dephosphorylation; regulation of JNK activity; regulation of MAP kinase activity

Research Articles on PPEF2

Similar Products

Product Notes

The PPEF2 ppef2 (Catalog #AAA9220757) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PPEF2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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