POC1A blocking peptide

POC1A Antibody (N-term) Blocking Peptide

• Gene Names: POC1A; PIX2; SOFT; WDR51A
• Synonyms: POC1A; POC1A Antibody (N-term) Blocking Peptide; POC1 centriolar protein homolog A; Pix2; Proteome of centriole protein 1A; WD repeat-containing protein 51A; WDR51A; POC1A blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 407

• Cellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole Note: Component of both mother and daughter centrioles
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for POC1A blocking peptide

Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation.

NCBI and Uniprot Product Information

• NCBI GI #: 91207986
• NCBI GeneID: 25886
• UniProt Accession #: Q8NBT0; Q0VDF8; Q2TAK6; Q96IK6; Q9UFJ8; A4FUW4; E9PFC6
• Molecular Weight: 40,936 Da
• NCBI Official Full Name: POC1 centriolar protein homolog A
• NCBI Official Synonym Full Names: POC1 centriolar protein A
• NCBI Official Symbol: POC1A
• NCBI Official Synonym Symbols: PIX2; SOFT; WDR51A
• NCBI Protein Information: POC1 centriolar protein homolog A
• UniProt Protein Name: POC1 centriolar protein homolog A
• Protein Family: POC1 centriolar protein
• UniProt Gene Name: POC1A
• UniProt Synonym Gene Names: WDR51A
• UniProt Entry Name: POC1A_HUMAN

NCBI Description

POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012]

Uniprot Description

WDR51A: POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome. [provided by RefSeq, Sep 2012]

Chromosomal Location of Human Ortholog: 3p21.2

Cellular Component: centriole; centrosome; spindle pole

Molecular Function: protein binding

Disease: Short Stature, Onychodysplasia, Facial Dysmorphism, And Hypotrichosis