PNPLA4 blocking peptide

PNPLA4 Antibody (C-term) Blocking peptide

• Gene Names: PNPLA4; GS2; DXS1283E; iPLA2eta
• Synonyms: PNPLA4; PNPLA4 Antibody (C-term) Blocking peptide; Patatin-like phospholipase domain-containing protein 4; Protein GS2; DXS1283E; GS2; PNPLA4 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the C-term region of PNPLA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 253

• Tissue Location: Expressed in all tissues examined, including heart, brain, placenta, lung, liver, muscle, kidney, pancreas and spleen.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for PNPLA4 blocking peptide

Lipid hydrolase.

NCBI and Uniprot Product Information

• NCBI GI #: 116242718
• NCBI GeneID: 8228
• UniProt Accession #: P41247; Q8WW83; A8K1H3; B4E362
• Molecular Weight: 18,629 Da
• NCBI Official Full Name: Patatin-like phospholipase domain-containing protein 4
• NCBI Official Synonym Full Names: patatin like phospholipase domain containing 4
• NCBI Official Symbol: PNPLA4
• NCBI Official Synonym Symbols: GS2; DXS1283E; iPLA2eta
• NCBI Protein Information: patatin-like phospholipase domain-containing protein 4
• UniProt Protein Name: Patatin-like phospholipase domain-containing protein 4
• Protein Family: Patatin-like phospholipase domain-containing protein
• UniProt Gene Name: PNPLA4
• UniProt Synonym Gene Names: DXS1283E; GS2
• UniProt Entry Name: PLPL4_HUMAN

NCBI Description

This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y. [provided by RefSeq, Feb 2010]

Uniprot Description

PNPLA4: Lipid hydrolase. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - retinol; Lipase; EC 3.1.1.3

Chromosomal Location of Human Ortholog: Xp22.3

Cellular Component: cytosol

Molecular Function: retinyl-palmitate esterase activity; triacylglycerol lipase activity

Biological Process: cellular lipid metabolic process