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Testing Data (The OmniKine Human CNTF ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CNTF proteins within the range of 47-3000 pg/ml.)

Human CNTF ELISA Kit | CNTF elisa kit

CNTF (Human) OmniKine ELISA Kit

Gene Names
CNTF; HCNTF
Reactivity
Human
Synonyms
CNTF; CNTF (Human) OmniKine ELISA Kit; Ciliary neurotrophic factor; CNTF elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
The OmniKine Human CNTF ELISA is capable of recognizing both recombinant and naturally produced Human CNTF proteins. The antigens listed below were tested at 50 ng/ml and exhibited 100% cross reactivity.
Rat: CNTF
The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: BNDF, beta-NGF, GDNF, NT-3, NT-4
Murine: beta-NGF, GDNF
Rat: GDNF
Form/Format
12 x 8-Well Microstrips
Sequence Length
200
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
47-3000 pg/ml
Sensitivity
47-3000 pg/ml
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human CNTF ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CNTF proteins within the range of 47-3000 pg/ml.)

Testing Data (The OmniKine Human CNTF ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CNTF proteins within the range of 47-3000 pg/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,931 Da
NCBI Official Full Name
ciliary neurotrophic factor
NCBI Official Synonym Full Names
ciliary neurotrophic factor
NCBI Official Symbol
CNTF
NCBI Official Synonym Symbols
HCNTF
NCBI Protein Information
ciliary neurotrophic factor
UniProt Protein Name
Ciliary neurotrophic factor
UniProt Gene Name
CNTF
UniProt Synonym Gene Names
CNTF

NCBI Description

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]

Uniprot Description

CNTF: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Belongs to the CNTF family.

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: axon; cytoplasm; extracellular region; extracellular space

Molecular Function: ciliary neurotrophic factor receptor binding; cytokine activity; growth factor activity; interleukin-6 receptor binding; protein binding

Biological Process: astrocyte activation; growth; muscle morphogenesis; negative regulation of neuron apoptosis; negative regulation of photoreceptor cell differentiation; neuron development; positive regulation of axon regeneration; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of STAT protein; regulation of retinal cell programmed cell death; signal transduction

Research Articles on CNTF

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Product Notes

The Human CNTF cntf (Catalog #AAA9501835) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501835 ELISA Kit recognizes Human CNTF. It is sometimes possible for the material contained within the vial of "CNTF, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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