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PLD3 blocking peptide

PLD3 Blocking Peptide(N-term)

Gene Names
PLD3; AD19; HUK4; HU-K4
Synonyms
PLD3; PLD3 Blocking Peptide(N-term); Phospholipase D3; PLD 3; Choline phosphatase 3; HindIII K4L homolog; Hu-K4; Phosphatidylcholine-hydrolyzing phospholipase D3; PLD3 blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 24-37 of HUMAN PLD3
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
490
Cellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location
Widely expressed. In the brain, high levels of expression are detected in the frontal, temporal and occipital cortices and hippocampus. Expressed at low level in corpus callosum.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PLD3 blocking peptide
Probably involved in APP processing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,705 Da
NCBI Official Full Name
phospholipase D3
NCBI Official Synonym Full Names
phospholipase D family member 3
NCBI Official Symbol
PLD3
NCBI Official Synonym Symbols
AD19; HUK4; HU-K4
NCBI Protein Information
phospholipase D3
UniProt Protein Name
Phospholipase D3
Protein Family
UniProt Gene Name
PLD3
UniProt Synonym Gene Names
PLD 3
UniProt Entry Name
PLD3_HUMAN

NCBI Description

This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]

Uniprot Description

PLD3: Belongs to the phospholipase D family.

Protein type: Endoplasmic reticulum; Membrane protein, integral; EC 3.1.4.4; Phospholipase

Chromosomal Location of Human Ortholog: 19q13.2

Molecular Function: protein binding

Disease: Alzheimer Disease 19

Research Articles on PLD3

Similar Products

Product Notes

The PLD3 pld3 (Catalog #AAA9228632) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PLD3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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