PIK3AP1 blocking peptide
PIK3AP1 Antibody (C-term) Blocking peptide
Gene Names
PIK3AP1; BCAP
Synonyms
PIK3AP1; PIK3AP1 Antibody (C-term) Blocking peptide; Phosphoinositide 3-kinase adapter protein 1; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1; BCAP; PIK3AP1 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
805
Cellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein
Tissue Location
Expressed in natural killer (NK) cells.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PIK3AP1 blocking peptide
Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
45,484 Da
NCBI Official Full Name
Phosphoinositide 3-kinase adapter protein 1
NCBI Official Synonym Full Names
phosphoinositide-3-kinase adaptor protein 1
NCBI Official Symbol
PIK3AP1
NCBI Official Synonym Symbols
BCAP
NCBI Protein Information
phosphoinositide 3-kinase adapter protein 1
UniProt Protein Name
Phosphoinositide 3-kinase adapter protein 1
Protein Family
UniProt Gene Name
PIK3AP1
UniProt Synonym Gene Names
BCAP
UniProt Entry Name
BCAP_HUMAN
Uniprot Description
BCAP: an adaptor protein for phosphoinositide-3-kinase. Plays a role in connecting B-cell antigen receptor signaling to phosphoinositide 3-kinase activation.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 10q24.1
Cellular Component: cytosol; membrane; plasma membrane
Biological Process: positive regulation of phosphoinositide 3-kinase cascade; regulation of inflammatory response; toll-like receptor 2 signaling pathway; toll-like receptor 4 signaling pathway; toll-like receptor 7 signaling pathway; toll-like receptor 9 signaling pathway
Research Articles on PIK3AP1
1. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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Product Notes
The PIK3AP1 pik3ap1 (Catalog #AAA9219466) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PIK3AP1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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