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PHC3 blocking peptide

PHC3 Blocking Peptide (C-Term)

Gene Names
PHC3; EDR3; HPH3
Synonyms
PHC3; PHC3 Blocking Peptide (C-Term); Polyhomeotic-like protein 3; Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3; EDR3; PH3; PHC3 blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 839-850 of HUMAN PHC3
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
983
Cellular Location
Nucleus
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PHC3 blocking peptide
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
107,480 Da
NCBI Official Full Name
Polyhomeotic-like protein 3
NCBI Official Synonym Full Names
polyhomeotic homolog 3
NCBI Official Symbol
PHC3
NCBI Official Synonym Symbols
EDR3; HPH3
NCBI Protein Information
polyhomeotic-like protein 3
UniProt Protein Name
Polyhomeotic-like protein 3
Protein Family
UniProt Gene Name
PHC3
UniProt Synonym Gene Names
EDR3; PH3; hPH3
UniProt Entry Name
PHC3_HUMAN

Uniprot Description

PHC3: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 3q26.2

Cellular Component: actin cytoskeleton; intracellular membrane-bound organelle; nucleoplasm; nucleus; PcG protein complex

Molecular Function: protein binding

Biological Process: protein sumoylation

Research Articles on PHC3

Similar Products

Product Notes

The PHC3 phc3 (Catalog #AAA9230458) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PHC3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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