PGCF blocking peptide
PGCF Peptide
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500
Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
NCBI and Uniprot Product Information
NCBI Description
an orphan membrane guanylyl cyclase [RGD, Feb 2006]
Uniprot Description
GUCY2F: Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein type: Guanylyl cyclase; Protein kinase, RGC; Kinase, protein; Lyase; Protein kinase, dual-specificity (receptor); EC 4.6.1.2; Receptor, misc.; Membrane protein, integral; Nucleotide Metabolism - purine; RGC group; RGC family
Cellular Component: guanylate cyclase complex, soluble; integral to membrane; membrane; plasma membrane
Molecular Function: adenylate cyclase activity; ATP binding; GTP binding; guanylate cyclase activity; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase activity
Biological Process: cGMP biosynthetic process; detection of light stimulus involved in visual perception; protein amino acid phosphorylation; receptor guanylyl cyclase signaling pathway
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Product Notes
The PGCF gucy2f (Catalog #AAA544258) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PGCF can be used in a range of immunoassay formats including, but not limited to, Immunodepletion, Immunocompetition. Confocal Microscopy||1:200 Immunocytochemistry: 1:200 Immunofluorescence: 1:200 Immunohistochemistry: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the PGCF gucy2f for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGCF, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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