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Western Blot (WB)

Rabbit PGCF Polyclonal Antibody | anti-PGCF antibody

PGCF Antibody Affinity Purified

Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
PGCF; Polyclonal Antibody; PGCF Antibody Affinity Purified; Particulate Guanylate Cyclase F antibody; anti-PGCF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.75-1.20 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
3545
Applicable Applications for anti-PGCF antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
Confocal Microscopy||1:200
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500
Immunogen
Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein.
Expression
Expressed only in the eye.
Molecular Function
Lyase
Structure
Belongs to the adenylyl cyclase-class-4/guanylyl cyclase family. Contains 1 guanylate cyclase domain. Contains 1 protein kinase domain.
Subcellular Location
Membrane; Single-pass type I membrane protein
Preparation and Storage
-20 degree C for long term storage

Western Blot (WB)

Western Blot (WB)

Immunofluorescence (IF)

Immunofluorescence (IF)
Related Product Information for anti-PGCF antibody
Affinity Purified Guanylyl Cyclase F Antibody
Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
Product Categories/Family for anti-PGCF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
124,411 Da
NCBI Official Full Name
Rattus norvegicus guanylyl cyclase (GC-E), complete cds
NCBI Official Synonym Full Names
guanylate cyclase 2E
NCBI Official Symbol
Gucy2e
NCBI Protein Information
guanylyl cyclase GC-E
UniProt Protein Name
Retinal guanylyl cyclase 2
UniProt Gene Name
Gucy2f
UniProt Synonym Gene Names
Guc2f; RETGC-2; GC-F; ROS-GC2
UniProt Entry Name
GUC2F_RAT

NCBI Description

an orphan membrane guanylyl cyclase [RGD, Feb 2006]

Uniprot Description

GUCY2F: Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Protein kinase, dual-specificity (receptor); Lyase; Receptor, misc.; EC 4.6.1.2; Kinase, protein; Guanylyl cyclase; Protein kinase, RGC; Nucleotide Metabolism - purine; Membrane protein, integral; RGC group; RGC family

Cellular Component: guanylate cyclase complex, soluble; integral to membrane; membrane; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; GTP binding; guanylate cyclase activity; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase activity

Biological Process: cGMP biosynthetic process; detection of light stimulus involved in visual perception; protein amino acid phosphorylation; receptor guanylyl cyclase signaling pathway

Similar Products

Product Notes

The PGCF gucy2f (Catalog #AAA540094) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGCF Antibody Affinity Purified reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PGCF can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). Confocal Microscopy||1:200 Dot Blot: 1:10,000 ELISA: 1:10,000 Immunocytochemistry: 1:200 Immunofluorescence: 1:200 Immunohistochemistry: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the PGCF gucy2f for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGCF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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