PAPD5 blocking peptide
PAPD5 Antibody (N-term) Blocking Peptide
Gene Names
PAPD5; TRF4-2
Synonyms
PAPD5; PAPD5 Antibody (N-term) Blocking Peptide; Non-canonical poly(A) RNA polymerase PAPD5; PAP-associated domain-containing protein 5; Terminal uridylyltransferase 3; TUTase 3; Topoisomerase-related function protein 4-2; TRF4-2; PAPD5 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
572
Cellular Location
Nucleus, nucleolus. Cytoplasm. Note: Predominantly expressed in the cytoplasm
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PAPD5 blocking peptide
Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
75,801 Da
NCBI Official Full Name
Non-canonical poly(A) RNA polymerase PAPD5
NCBI Official Synonym Full Names
poly(A) RNA polymerase D5, non-canonical
NCBI Official Symbol
PAPD5
NCBI Official Synonym Symbols
TRF4-2
NCBI Protein Information
non-canonical poly(A) RNA polymerase PAPD5
UniProt Protein Name
Non-canonical poly(A) RNA polymerase PAPD5
Protein Family
UniProt Gene Name
PAPD5
UniProt Synonym Gene Names
TUTase 3; TRF4-2
UniProt Entry Name
PAPD5_HUMAN
Uniprot Description
PAPD5: Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Belongs to the DNA polymerase type-B-like family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.7.19; Nucleolus; Transferase
Chromosomal Location of Human Ortholog: 16q12.1
Research Articles on PAPD5
Similar Products
Product Notes
The PAPD5 papd5 (Catalog #AAA9223443) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PAPD5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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