OBCAM blocking peptide

OBCAM (E201) Peptide

Cat. Num. AAA3003108

• Gene Names: OPCML; OPCM; OBCAM; IGLON1
• Applications: Blocking
• Purity: Synthetic peptide OBCAM (E201). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Synonyms: OBCAM; OBCAM (E201) Peptide; Opioid-binding protein/cell adhesion molecule; OPCML; Opioid-binding cell adhesion molecule; IgLON family member 1; IGLON1; OBCAM blocking peptide

• Specificity: This peptide can be used with studies using MBS3003107 OBCAM (E201) pAb.
• Purity/Purification: Synthetic peptide OBCAM (E201). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Form/Format: 1 mg/ml in DI water.
• Sequence Length: 345

• Applicable Applications for OBCAM blocking peptide: Blocking
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Related Product Information for OBCAM blocking peptide

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems.

NCBI and Uniprot Product Information

• NCBI GI #: 2497326
• NCBI GeneID: 4978
• UniProt Accession #: Q14982
• NCBI Official Full Name: Opioid-binding protein/cell adhesion molecule
• NCBI Official Synonym Full Names: opioid binding protein/cell adhesion molecule like
• NCBI Official Symbol: OPCML
• NCBI Official Synonym Symbols: OPCM; OBCAM; IGLON1
• NCBI Protein Information: opioid-binding protein/cell adhesion molecule
• UniProt Protein Name: Opioid-binding protein/cell adhesion molecule
• UniProt Gene Name: OPCML
• UniProt Synonym Gene Names: IGLON1; OBCAM; OBCAM; OPCML; Opioid-binding cell adhesion molecule
• UniProt Entry Name: OPCM_HUMAN

NCBI Description

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Uniprot Description

OPCML: Binds opioids in the presence of acidic lipids; probably involved in cell contact. Defects in OPCML are a cause of susceptibility to ovarian cancer (OC). Ovarian cancer common malignancy originating from ovarian tissue. Although many histologic types of ovarian neoplasms have been described, epithelial ovarian carcinoma is the most common form. Ovarian cancers are often asymptomatic and the recognized signs and symptoms, even of late- stage disease, are vague. Consequently, most patients are diagnosed with advanced disease. Belongs to the immunoglobulin superfamily. IgLON family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 11q25

Cellular Component: neuron projection; cell surface; cell soma; plasma membrane; intercellular junction

Biological Process: cell-cell adhesion; regulation of neurogenesis; neuron recognition; cell adhesion

Disease: Ovarian Cancer