NPRL3 blocking peptide
NPRL3 Blocking Peptide (N-Term)
Gene Names
NPRL3; MARE; NPR3; HS-40; RMD11; CGTHBA; C16orf35
Synonyms
NPRL3; NPRL3 Blocking Peptide (N-Term); Nitrogen permease regulator 3-like protein; -14 gene protein; Alpha-globin regulatory element-containing gene protein; Protein CGTHBA; C16orf35; CGTHBA; MARE; NPRL3 blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 106-117 of HUMAN NPRL3
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
569
Tissue Location
Widely expressed.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for NPRL3 blocking peptide
As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
63,605 Da
NCBI Official Full Name
Nitrogen permease regulator 3-like protein
NCBI Official Synonym Full Names
NPR3 like, GATOR1 complex subunit
NCBI Official Symbol
NPRL3
NCBI Official Synonym Symbols
MARE; NPR3; HS-40; RMD11; CGTHBA; C16orf35
NCBI Protein Information
nitrogen permease regulator 3-like protein
UniProt Protein Name
Nitrogen permease regulator 3-like protein
UniProt Gene Name
NPRL3
UniProt Synonym Gene Names
C16orf35; CGTHBA; MARE
UniProt Entry Name
NPRL3_HUMAN
NCBI Description
The function of the encoded protein is not known. [provided by RefSeq, Aug 2011]
Uniprot Description
NPRL3: The function of the encoded protein is not known. [provided by RefSeq, Aug 2011]
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 16p13.3
Molecular Function: GTPase activator activity
Biological Process: cellular response to amino acid starvation; negative regulation of TOR signaling pathway
Research Articles on NPRL3
Similar Products
Product Notes
The NPRL3 nprl3 (Catalog #AAA9230472) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NPRL3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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