NDUFB3 blocking peptide

NDUFB3 Blocking Peptide (N-Term)

Gene Names

NDUFB3; B12; CI-B12

Synonyms

NDUFB3; NDUFB3 Blocking Peptide (N-Term); NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3; Complex I-B12; CI-B12; NADH-ubiquinone oxidoreductase B12 subunit; NDUFB3 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 13-45 of HUMAN NDUFB3

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

Cellular Location

Mitochondrion inner membrane; Single-pass membrane protein; Matrix side

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for NDUFB3 blocking peptide

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

NCBI and Uniprot Product Information

NCBI GI #

6093472

NCBI GeneID

4709

UniProt Accession #

O43676; Q6IB80

Molecular Weight

11,402 Da

NCBI Official Full Name

NADH dehydrogenase

NCBI Official Synonym Full Names

NADH:ubiquinone oxidoreductase subunit B3

NCBI Official Symbol

NDUFB3

NCBI Official Synonym Symbols

B12; CI-B12

NCBI Protein Information

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

UniProt Protein Name

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

Protein Family

NADH dehydrogenase

UniProt Gene Name

NDUFB3

UniProt Synonym Gene Names

CI-B12

UniProt Entry Name

NDUB3_HUMAN

NCBI Description

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]

Uniprot Description

NDUFB3: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFB3 subunit family.

Protein type: Oxidoreductase; EC 1.6.99.3; Mitochondrial; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; EC 1.6.5.3

Chromosomal Location of Human Ortholog: 2q31.3

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I

Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly

Disease: Mitochondrial Complex I Deficiency

Research Articles on NDUFB3

1. Recessive mutations in NDUFB3 cause complex I deficiency

Similar Products

Product Notes

The NDUFB3 ndufb3 (Catalog #AAA9230374) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NDUFB3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Loading...

NDUFB3 blocking peptide