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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7048744 at dilution of 1:100)

Rabbit anti-Human NDUFB3 Polyclonal Antibody | anti-NDUFB3 antibody

NDUFB3 Antibody

Gene Names
NDUFB3; B12; CI-B12
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
NDUFB3; Polyclonal Antibody; NDUFB3 Antibody; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3; Complex I-B12; CI-B12; NADH-ubiquinone oxidoreductase B12 subunit; anti-NDUFB3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
98
Applicable Applications for anti-NDUFB3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1: 20-1: 200
Immunogen
Recombinant Human NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 protein (2-65AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-135317
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7048744 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7048744 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7048744 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver tissue using MBS7048744 at dilution of 1:100)
Related Product Information for anti-NDUFB3 antibody
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,402 Da
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH:ubiquinone oxidoreductase subunit B3
NCBI Official Symbol
NDUFB3
NCBI Official Synonym Symbols
B12; CI-B12
NCBI Protein Information
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
UniProt Protein Name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Protein Family
UniProt Gene Name
NDUFB3
UniProt Synonym Gene Names
CI-B12
UniProt Entry Name
NDUB3_HUMAN

NCBI Description

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]

Uniprot Description

NDUFB3: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFB3 subunit family.

Protein type: EC 1.6.5.3; EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 2q31.3

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I

Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly

Disease: Mitochondrial Complex I Deficiency

Research Articles on NDUFB3

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Product Notes

The NDUFB3 ndufb3 (Catalog #AAA7048744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NDUFB3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NDUFB3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1: 20-1: 200. Researchers should empirically determine the suitability of the NDUFB3 ndufb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDUFB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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