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NDST4 blocking peptide

NDST4 Antibody (N-term) Blocking Peptide

Gene Names
NDST4; N-HSST; NDST-4; NHSST4; N-HSST 4
Synonyms
NDST4; NDST4 Antibody (N-term) Blocking Peptide; Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; Glucosaminyl N-deacetylase/N-sulfotransferase 4; NDST-4; N-heparan sulfate sulfotransferase 4; N-HSST 4; Heparan sulfate N-deacetylase 4; 3---; Heparan sulfate N-sulfotransferase 4; 282-; HSST4; NDST4 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
872
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for NDST4 blocking peptide
Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
42,852 Da
NCBI Official Full Name
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
NCBI Official Synonym Full Names
N-deacetylase and N-sulfotransferase 4
NCBI Official Symbol
NDST4
NCBI Official Synonym Symbols
N-HSST; NDST-4; NHSST4; N-HSST 4
NCBI Protein Information
bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
UniProt Protein Name
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
UniProt Gene Name
NDST4
UniProt Synonym Gene Names
HSST4; NDST-4; N-HSST 4
UniProt Entry Name
NDST4_HUMAN

Uniprot Description

NDST4: Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity. Belongs to the sulfotransferase 1 family. NDST subfamily.

Protein type: Transferase; EC 2.8.2.8; Glycan Metabolism - heparan sulfate biosynthesis; Hydrolase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q26

Research Articles on NDST4

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Product Notes

The NDST4 ndst4 (Catalog #AAA9223132) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NDST4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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