Mouse anti-Human NDST4 Polyclonal Antibody | anti-NDST4 antibody

NDST4 (HSST4, Bifunctional Heparan Sulfate N-deacetylase/N-sulfotransferase 4, Glucosaminyl N-deacetylase/N-sulfotransferase 4, N-heparan Sulfate Sulfotransferase 4, Heparan Sulfate N-deacetylase 4, Heparan Sulfate N-sulfotransferase 4)

Cat. Num. AAA642999

• Gene Names: NDST4; NDST-4; NHSST4
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: NDST4; Polyclonal Antibody; NDST4 (HSST4; Bifunctional Heparan Sulfate N-deacetylase/N-sulfotransferase 4; Glucosaminyl N-deacetylase/N-sulfotransferase 4; N-heparan Sulfate Sulfotransferase 4; Heparan Sulfate N-deacetylase 4; Heparan Sulfate N-sulfotransferase 4); Anti -NDST4 (HSST4; anti-NDST4 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human NDST4.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MNLIVKLRRSFRTLIVLLATFCLVSIVISAYFLYSGYKQEMTLIETTAEAECTDIKILPYRSMELKTVKPIDTSKTDPTVLLFVESQYSQLGQDIIAILESSRFQYHMVIAPGKGDIPPLTDNGKGKYTLVIYENILKYVSMDSWNRELLEKYCVEYSVSIIGFHKANENSLPSTQLKGFPLNLFNNLALKDCFVNPQSPLLHITKAPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQTEKSLSSLSSKTLFATVIQDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDEGDDLLLRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINMGYAVAPHHSGVYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIRGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLVNFVQSWTNLKLQTLPPVQLAHQYFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLVIGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTPSNTTSDFLFEKSANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVISTGHWAPSDLKTLQRRCLVPGWYAVHIERWLTYFATSQLLIIDGQQLRSDPATVMDEVQKFLGVTPRYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLSNYYRDHNVELSKLLHRLGQPLPSWLRQELQKVR

• Applicable Applications for anti-NDST4 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human NDST4, aa1-872 (NP_072091.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of NDST4 expression in transfected 293T cell line by NDST4 polyclonal antibody. Lane 1: NDST4 transfected lysate (95.92kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-NDST4 antibody

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity).

Product Categories/Family for anti-NDST4 antibody

Antibodies; Abs to Enzymes; Sulfotransferase

NCBI and Uniprot Product Information

• NCBI GI #: 86577748
• NCBI GeneID: 64579
• UniProt Accession #: Q9H3R1
• Molecular Weight: 100,716 Da
• NCBI Official Full Name: NDST4 protein
• NCBI Official Synonym Full Names: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
• NCBI Official Symbol: NDST4
• NCBI Official Synonym Symbols: NDST-4; NHSST4
• NCBI Protein Information: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; N-HSST 4; N-heparan sulfate sulfotransferase 4; glucosaminyl N-deacetylase/N-sulfotransferase 4
• UniProt Protein Name: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
• Protein Family: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase
• UniProt Gene Name: NDST4
• UniProt Synonym Gene Names: HSST4; NDST-4; N-HSST 4
• UniProt Entry Name: NDST4_HUMAN

Uniprot Description

NDST4: Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity. Belongs to the sulfotransferase 1 family. NDST subfamily.

Protein type: EC 2.8.2.8; Glycan Metabolism - heparan sulfate biosynthesis; Hydrolase; Transferase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q26

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: deacetylase activity; [heparan sulfate]-glucosamine N-sulfotransferase activity

Biological Process: heparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process