Med15 blocking peptide

Med15 Blocking Peptide (C-term)

Gene Names

Med15; Pcqap; mPcqap; AW536074; A230074L19Rik

Synonyms

Med15; Med15 Blocking Peptide (C-term); Mediator of RNA polymerase II transcription subunit 15; Mediator complex subunit 15; Positive cofactor 2 glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; mPcqap; Pcqap; Med15 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 743-759 of HUMAN Med15

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

792

Cellular Location

Cytoplasm. Nucleus

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for Med15 blocking peptide

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity).

NCBI and Uniprot Product Information

NCBI GI #

20177999

NCBI GeneID

94112

UniProt Accession #

Q924H2

Molecular Weight

87,061 Da

NCBI Official Full Name

Mediator of RNA polymerase II transcription subunit 15

NCBI Official Synonym Full Names

mediator complex subunit 15

NCBI Official Symbol

Med15

NCBI Official Synonym Symbols

Pcqap; mPcqap; AW536074; A230074L19Rik

NCBI Protein Information

mediator of RNA polymerase II transcription subunit 15

UniProt Protein Name

Mediator of RNA polymerase II transcription subunit 15

Protein Family

Mediator of RNA polymerase II transcription

UniProt Gene Name

Med15

UniProt Synonym Gene Names

Pcqap; PC2 glutamine/Q-rich-associated protein; mPcqap

UniProt Entry Name

MED15_MOUSE

Uniprot Description

PCQAP: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway. Belongs to the Mediator complex subunit 15 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Cellular Component: Srb-mediator complex

Biological Process: stem cell maintenance

Similar Products

Product Notes

The Med15 med15 (Catalog #AAA9229903) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Med15, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Med15 blocking peptide