LSM2 blocking peptide

LSM2 Blocking Peptide (C-Term)

Gene Names

LSM2; G7B; snRNP; C6orf28; YBL026W

Synonyms

LSM2; LSM2 Blocking Peptide (C-Term); U6 snRNA-associated Sm-like protein LSm2; Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP core Sm-like protein Sm-x5; C6orf28; G7B; LSM2 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 75-89 of HUMAN LSM2

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

Cellular Location

Nucleus.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for LSM2 blocking peptide

Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.

NCBI and Uniprot Product Information

NCBI GI #

10720079

NCBI GeneID

57819

UniProt Accession #

Q9Y333; Q6FGG1

Molecular Weight

10,835 Da

NCBI Official Full Name

U6 snRNA-associated Sm-like protein LSm2

NCBI Official Synonym Full Names

LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated

NCBI Official Symbol

LSM2

NCBI Official Synonym Symbols

G7B; snRNP; C6orf28; YBL026W

NCBI Protein Information

U6 snRNA-associated Sm-like protein LSm2

UniProt Protein Name

U6 snRNA-associated Sm-like protein LSm2

Protein Family

Sm-like protein

UniProt Gene Name

LSM2

UniProt Synonym Gene Names

C6orf28; G7B

UniProt Entry Name

LSM2_HUMAN

NCBI Description

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]

Uniprot Description

LSM2: Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing. Identified in the spliceosome C complex. LSm subunits form a heteromer with a doughnut shape. Belongs to the snRNP Sm proteins family.

Protein type: RNA splicing; Spliceosome; RNA-binding

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: cytosol; nucleoplasm; U4/U6 x U5 tri-snRNP complex

Molecular Function: protein binding; Ral GTPase binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome

Research Articles on LSM2

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

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Product Notes

The LSM2 lsm2 (Catalog #AAA9230347) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LSM2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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LSM2 blocking peptide