LIV-1/ZIP6 blocking peptide

LIV-1/ZIP6 Blocking Peptide

Gene Names

SLC39A6; ZIP6; LIV-1

Applications

Blocking/Control

Purity

The purity is >90%,tested by HPLC and MS.

Synonyms

LIV-1/ZIP6; LIV-1/ZIP6 Blocking Peptide; Estrogen regulated protein LIV 1 6; Estrogen-regulated protein LIV-1; LIV 1; LIV 1 protein; estrogen regulated; S39A6_HUMAN; SLC39A6; Solute carrier family 39 (metal ion transporter); member 6; solute carrier family 39 (zinc transporter); Solute carrier family 39 member 6; Zinc transporter ZIP6; ZIP 6; ZIP-6; Zrt and Irt like protein 6; Zrt-and Irt-like protein 6; LIV-1/ZIP6 blocking peptide

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Cat. Num. AAA9621125 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Applicable Applications for LIV-1/ZIP6 blocking peptide

Blocking/Control

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for LIV-1/ZIP6 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

NCBI GI #

153252214

NCBI GeneID

25800

NCBI Accession #

NP_001092876.1

NCBI GenBank Nucleotide #

NM_001099406.1

UniProt Accession #

Q13433; Q8IXR3; Q96HP5; B4DR49; B4E224

Molecular Weight

48,605 Da

NCBI Official Full Name

zinc transporter ZIP6 isoform 2

NCBI Official Synonym Full Names

solute carrier family 39 member 6

NCBI Official Symbol

SLC39A6

NCBI Official Synonym Symbols

ZIP6; LIV-1

NCBI Protein Information

zinc transporter ZIP6

UniProt Protein Name

Zinc transporter ZIP6

UniProt Gene Name

SLC39A6

UniProt Synonym Gene Names

LIV1; ZIP6; ZIP-6

UniProt Entry Name

S39A6_HUMAN

NCBI Description

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

Uniprot Description

SLC39A6: May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 18q12.2

Cellular Component: cell surface; integral to plasma membrane; endoplasmic reticulum; plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: cellular zinc ion homeostasis; transmembrane transport

Research Articles on LIV-1/ZIP6

1. Upregulation of SLC39A6 is associated with hepatocellular carcinoma.

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Product Notes

The LIV-1/ZIP6 slc39a6 (Catalog #AAA9621125) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LIV-1/ZIP6 can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the LIV-1/ZIP6 slc39a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIV-1/ZIP6, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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LIV-1/ZIP6 blocking peptide