IL4I1 blocking peptide

IL4I1 Blocking Peptide (C-Term)

Gene Names

IL4I1; LAO; FIG1; LAAO

Synonyms

IL4I1; IL4I1 Blocking Peptide (C-Term); L-amino-acid oxidase; LAAO; LAO; 1.4.3.2; Interleukin-4-induced protein 1; IL4-induced protein 1; Protein Fig-1; hFIG1; FIG1; IL4I1 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 411-422 of HUMAN IL4I1

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

567

Cellular Location

Isoform 1: Lysosome.

Tissue Location

Isoform 1 is primarily found in immune tissues.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for IL4I1 blocking peptide

Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity).

NCBI and Uniprot Product Information

NCBI GI #

20138284

NCBI GeneID

259307

UniProt Accession #

Q96RQ9; Q1WMJ3; Q4GZN1; Q4GZN2; Q6P2Q3; Q8TEM5; Q96RQ8

Molecular Weight

65,328 Da

NCBI Official Full Name

L-amino-acid oxidase

NCBI Official Synonym Full Names

interleukin 4 induced 1

NCBI Official Symbol

IL4I1

NCBI Official Synonym Symbols

LAO; FIG1; LAAO

NCBI Protein Information

L-amino-acid oxidase

UniProt Protein Name

L-amino-acid oxidase

UniProt Gene Name

IL4I1

UniProt Synonym Gene Names

FIG1; LAAO; LAO; IL4-induced protein 1; hFIG1

UniProt Entry Name

OXLA_HUMAN

NCBI Description

This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Uniprot Description

IL4I1: Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation. Belongs to the flavin monoamine oxidase family. FIG1 subfamily. 2 isoforms of the human protein are produced by alternative promoter.

Protein type: Amino Acid Metabolism - cysteine and methionine; Secreted; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - phenylalanine; Secreted, signal peptide; Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; EC 1.4.3.2; Oxidoreductase

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: extracellular region

Molecular Function: L-amino-acid oxidase activity

Biological Process: L-phenylalanine catabolic process

Research Articles on IL4I1

1. The immunosuppressive enzyme IL4I1 expressed differentially in human induced Aiolos+, but not natural Helios+, FOXP3+ Treg cells.

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Product Notes

The IL4I1 il4i1 (Catalog #AAA9230598) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IL4I1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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IL4I1 blocking peptide