GNAZ blocking peptide

GNAZ Antibody (N-term) Blocking Peptide

• Synonyms: GNAZ; GNAZ Antibody (N-term) Blocking Peptide; Guanine nucleotide-binding protein G(z) subunit alpha; G(x) alpha chain; Gz-alpha; GNAZ blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 355

• Cellular Location: Membrane; Lipid-anchor.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for GNAZ blocking peptide

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

NCBI and Uniprot Product Information

• NCBI GI #: 121005
• NCBI GeneID: 2781
• UniProt Accession #: P19086; Q4QRJ6; B2R6C1
• Molecular Weight: 40,924 Da
• NCBI Official Full Name: Guanine nucleotide-binding protein G(z) subunit alpha
• NCBI Official Synonym Full Names: G protein subunit alpha z
• NCBI Official Symbol: GNAZ
• NCBI Protein Information: guanine nucleotide-binding protein G(z) subunit alpha
• UniProt Protein Name: Guanine nucleotide-binding protein G(z) subunit alpha
• UniProt Gene Name: GNAZ
• UniProt Entry Name: GNAZ_HUMAN

NCBI Description

The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008]

Uniprot Description

G-alpha(z): Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Protein type: Nuclear envelope; Endoplasmic reticulum; G protein, heterotrimeric alpha G((i/o/t/z)); G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 22q11.22

Cellular Component: endoplasmic reticulum; heterotrimeric G-protein complex; nuclear envelope; plasma membrane

Molecular Function: G-protein beta/gamma-subunit binding; GTP binding; GTPase activity; metabotropic serotonin receptor binding; receptor signaling protein activity

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; protein folding