Rabbit anti-Human GNAZ Polyclonal Antibody | anti-GNAZ antibody

GNAZ Antibody

Cat. Num. AAA7048289

• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Immunofluorescence
• Purity: >95%, Protein G purified
• Synonyms: GNAZ; Polyclonal Antibody; GNAZ Antibody; Guanine nucleotide-binding protein G(z) subunit alpha; G(x) alpha chain; Gz-alpha; anti-GNAZ antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 355

• Applicable Applications for anti-GNAZ antibody: ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: IHC: 1: 20-1: 200; IF: 1: 50-1: 200
• Immunogen: Recombinant Human Guanine nucleotide-binding protein G(z) subunit alpha protein (3-140AA)
• Preservative: 0.03% Proclin 300
• Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Conjugation: Non-conjugated
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26770 / sc-388
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7048289 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of Hela cells using MBS7048289 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-GNAZ antibody

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

NCBI and Uniprot Product Information

• NCBI GI #: 4504051
• NCBI GeneID: 2781
• NCBI Accession #: NP_002064.1
• NCBI GenBank Nucleotide #: NM_002073.2
• UniProt Accession #: P19086; Q4QRJ6; B2R6C1
• Molecular Weight: 40,924 Da
• NCBI Official Full Name: guanine nucleotide-binding protein G(z) subunit alpha
• NCBI Official Synonym Full Names: G protein subunit alpha z
• NCBI Official Symbol: GNAZ
• NCBI Protein Information: guanine nucleotide-binding protein G(z) subunit alpha
• UniProt Protein Name: Guanine nucleotide-binding protein G(z) subunit alpha
• UniProt Gene Name: GNAZ
• UniProt Entry Name: GNAZ_HUMAN

NCBI Description

The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008]

Uniprot Description

G-alpha(z): Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Protein type: Endoplasmic reticulum; G protein, heterotrimeric; G protein, heterotrimeric alpha G((i/o/t/z)); Nuclear envelope

Chromosomal Location of Human Ortholog: 22q11.22

Cellular Component: endoplasmic reticulum; heterotrimeric G-protein complex; nuclear envelope; plasma membrane

Molecular Function: G-protein beta/gamma-subunit binding; GTP binding; GTPase activity; metabotropic serotonin receptor binding; receptor signaling protein activity

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; protein folding