CYP4X1 blocking peptide

CYP4X1 Antibody (N-term) Blocking Peptide

• Gene Names: CYP4X1; CYPIVX1
• Synonyms: CYP4X1; CYP4X1 Antibody (N-term) Blocking Peptide; Cytochrome P450 4X1; CYPIVX1; CYP4X1 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human CYP4X1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 509

• Cellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein Microsome membrane
• Tissue Location: Expressed in brain, heart and kidney and, at lower levels, in skeletal muscle and liver. In the heart, very high level levels in aorta, but very levels in other heart regions.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 48428082
• NCBI GeneID: 260293
• UniProt Accession #: Q8N118; Q5VVE5; Q6ZN67; Q8NAZ3; G3V1U1
• Molecular Weight: 50,944 Da
• NCBI Official Full Name: Cytochrome P450 4X1
• NCBI Official Synonym Full Names: cytochrome P450 family 4 subfamily X member 1
• NCBI Official Symbol: CYP4X1
• NCBI Official Synonym Symbols: CYPIVX1
• NCBI Protein Information: cytochrome P450 4X1
• UniProt Protein Name: Cytochrome P450 4X1
• Protein Family: Cytochrome
• UniProt Gene Name: CYP4X1
• UniProt Entry Name: CP4X1_HUMAN

NCBI Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Uniprot Description

CYP4X1: a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. [provided by RefSeq, Jul 2008]

Protein type: Oxidoreductase; EC 1.14.14.1

Chromosomal Location of Human Ortholog: 1p33|1